Don’t get cute. Please, just don’t do it. If you have one of the best players in the NFL, but he’s had a couple of down games, don’t bench him for some guy who had one good week. That’s a surefire way to hate yourself later. I’ve been there and done that. “Hey, maybe I should bench Julio Jones because he’s only gotten 5 and 6 points the last 2 weeks.” No… no, you shouldn’t because as soon as you do, he’s going to have 250 yards and 2 touchdowns, and you’re going to look like a dope for starting Jamison Crowder because he had a couple great games in a row.
It’s easy to overthink when setting fantasy lineups. Obviously, you want to always look and see what you can do to make your team better, but overanalyzing can turn into an issue. If players are similar, definitely look at every factor to determine whether or not to start each one, but please don’t consider benching Antonio Brown because he doesn’t have the best matchup.